Based on the Universal movie starring Hugh Jackman, Van Helsing recreates battles from the film and adds additional backstory not shown in the theatrical release. The game takes place in Transylvania and has players progress through Castle Frankenstein and Castle Dracula. Within this horror movie world, Van Helsing encounters several monsters from Universal Studios' archives. Dracula, the Wolf Man, Frankenstein, Igor, and Dr. Jekyll are Just some of the licensed characters the monster hunter encounters and fights, along with hordes of original creatures made for the game. Van Helsing himself is equipped with several weapons, including his signature grappling hook that will work like Indiana Jones' whip, useful both as a tool to move around and a weapon.